Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 11 Reviews
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Lysine (from 637 mg L-Lysine Hydrochloride)
500 mg
**
Top Medical Research Studies
9
L-lysine may slow atherosclerosis
We explored how L-lysine, specifically the iNOS inhibitor N-iminoethyl-L-lysine (L-NIL), affects the progression of atherosclerosis in rabbits with high cholesterol. In our controlled study, we compared rabbits treated with L-NIL, a vehicle, or L-arginine after being fed a cholesterol-rich diet.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
Read More
8
We investigated a newly developed human antibody called FAP2M21 that targets PCSK9, a protein that affects cholesterol levels. This antibody has shown excellent binding properties and can effectively inhibit the reduction of LDL cholesterol uptake in liver cells.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
Read More
8
We examined the impact of L-lysine, delivered via a special method, on reducing high cholesterol. The study involved using a specific type of siRNA to target apolipoprotein B in mice.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Read More
Most Useful Reviews
9
Lowers cholesterol
102 people found this helpful
Perfectly reduces high cholesterol! The amino acid lysine aids in collagen formation and carbohydrate metabolism. It also inhibits the herpes simplex virus's growth and improves calcium absorption, significantly lowering osteoporosis risk. Lysine reduces serum triglycerides, thereby lowering cholesterol levels.
Read More
9
Herpes solution
11 people found this helpful
If you suffer from herpes, lysine is the answer! I experienced attacks every 20 days until I started taking a gram twice daily. Since then, I've had no flare-ups for three months. The quality of Now’s product is excellent, although the capsules are a bit large.
Read More
8
Effective remedy
10 people found this helpful
This high-quality remedy for herpes has worked wonders for me. I went from monthly outbreaks to just once a year after taking one 500 mg tablet before breakfast for three months. It also helped cure my cold quickly. Large packaging offers great value.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
- All Researches
9
L-lysine may slow atherosclerosis
We explored how L-lysine, specifically the iNOS inhibitor N-iminoethyl-L-lysine (L-NIL), affects the progression of atherosclerosis in rabbits with high cholesterol. In our controlled study, we compared rabbits treated with L-NIL, a vehicle, or L-arginine after being fed a cholesterol-rich diet.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
Read More
8
We investigated a newly developed human antibody called FAP2M21 that targets PCSK9, a protein that affects cholesterol levels. This antibody has shown excellent binding properties and can effectively inhibit the reduction of LDL cholesterol uptake in liver cells.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
Read More
8
We examined the impact of L-lysine, delivered via a special method, on reducing high cholesterol. The study involved using a specific type of siRNA to target apolipoprotein B in mice.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Read More
7
We investigated how high-protein diets and leucine supplementation impact mice, focusing on energy balance and body composition over 14 weeks.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Lowers cholesterol
102 people found this helpful
Perfectly reduces high cholesterol! The amino acid lysine aids in collagen formation and carbohydrate metabolism. It also inhibits the herpes simplex virus's growth and improves calcium absorption, significantly lowering osteoporosis risk. Lysine reduces serum triglycerides, thereby lowering cholesterol levels.
Read More
9
Herpes solution
11 people found this helpful
If you suffer from herpes, lysine is the answer! I experienced attacks every 20 days until I started taking a gram twice daily. Since then, I've had no flare-ups for three months. The quality of Now’s product is excellent, although the capsules are a bit large.
Read More
8
Effective remedy
10 people found this helpful
This high-quality remedy for herpes has worked wonders for me. I went from monthly outbreaks to just once a year after taking one 500 mg tablet before breakfast for three months. It also helped cure my cold quickly. Large packaging offers great value.
Read More
9
Carnitine production
Regular use of L-Lysine has reduced my herpes outbreaks. It also aids in carnitine production, converting amino acids into energy and lowering my high cholesterol levels. Additionally, it plays a key role in calcium absorption and collagen production.
Read More
7.5
Supports immunity
I bought NOW Foods L-Lysine to support my immune system and tackle herpes, and I am very pleased with the results! It significantly reduces outbreak frequency and severity. The tablets are high quality and easy to swallow, making them economical.
Read More
Frequently Asked Questions
8
Effective remedy
10 people found this helpful
This high-quality remedy for herpes has worked wonders for me. I went from monthly outbreaks to just once a year after taking one 500 mg tablet before breakfast for three months. It also helped cure my cold quickly. Large packaging offers great value.
7.5
Improves absorption
4 people found this helpful
Lysine inhibits the herpes simplex virus's growth, improves calcium absorption, significantly lowering osteoporosis risk, and reduces serum triglycerides, thus lowering cholesterol. If my review was useful, please give it a thumbs up.
7.5
Supports immunity
I bought NOW Foods L-Lysine to support my immune system and tackle herpes, and I am very pleased with the results! It significantly reduces outbreak frequency and severity. The tablets are high quality and easy to swallow, making them economical.
9
Herpes solution
11 people found this helpful
If you suffer from herpes, lysine is the answer! I experienced attacks every 20 days until I started taking a gram twice daily. Since then, I've had no flare-ups for three months. The quality of Now’s product is excellent, although the capsules are a bit large.
9
Lowers cholesterol
102 people found this helpful
Perfectly reduces high cholesterol! The amino acid lysine aids in collagen formation and carbohydrate metabolism. It also inhibits the herpes simplex virus's growth and improves calcium absorption, significantly lowering osteoporosis risk. Lysine reduces serum triglycerides, thereby lowering cholesterol levels.
7.5
Highly effective
3 people found this helpful
This is my go-to remedy for herpes! I've purchased L-lysine from Now Foods multiple times. The effectiveness is unmatched compared to other brands. I follow the recommended dosage, and it has boosted my energy during training while also assisting with cholesterol levels.
8
We investigated a newly developed human antibody called FAP2M21 that targets PCSK9, a protein that affects cholesterol levels. This antibody has shown excellent binding properties and can effectively inhibit the reduction of LDL cholesterol uptake in liver cells.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
In experiments with mice, administering FAP2M21 significantly reduced serum LDL cholesterol levels, depending on the dosage.
While the results indicate the antibody could be a strong candidate for treating high cholesterol, further studies will be necessary to fully understand its potential in humans.
8
We examined the impact of L-lysine, delivered via a special method, on reducing high cholesterol. The study involved using a specific type of siRNA to target apolipoprotein B in mice.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
Our findings showed a successful reduction in harmful LDL cholesterol levels in genetically modified mice, without any signs of liver damage. However, significant effects in wider populations remain unclear.
9
L-lysine may slow atherosclerosis
We explored how L-lysine, specifically the iNOS inhibitor N-iminoethyl-L-lysine (L-NIL), affects the progression of atherosclerosis in rabbits with high cholesterol. In our controlled study, we compared rabbits treated with L-NIL, a vehicle, or L-arginine after being fed a cholesterol-rich diet.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
The results were promising; L-NIL limited the progression of atherosclerosis in the rabbits. We observed notable differences in arterial health, with less disease advancement in the L-NIL group compared to the control groups. L-arginine showed some benefits, but not to the same extent as L-NIL.
7
We investigated how high-protein diets and leucine supplementation impact mice, focusing on energy balance and body composition over 14 weeks.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
Interestingly, we found that neither high-protein diets nor leucine supplementation influenced body weight, energy expenditure, or protein expression in the muscle.
However, plasma cholesterol levels significantly dropped in the high-protein and leucine-supplemented groups compared to those on a standard diet. Yet, there were concerns, such as increased triglycerides in the high-protein group.
Overall, while cholesterol levels showed some promise, the effects were not as widespread as we had hoped.
References
- Xu M, Lei G, Chen M, Wang K, Lv W, et al. Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy. EBioMedicine. 2021;65:103250. doi:10.1016/j.ebiom.2021.103250
- Noatsch A, Petzke KJ, Millrose MK, Klaus S. Body weight and energy homeostasis was not affected in C57BL/6 mice fed high whey protein or leucine-supplemented low-fat diets. Eur J Nutr. 2011;50:479. doi:10.1007/s00394-010-0155-2
- Watanabe K, Harada-Shiba M, Suzuki A, Gokuden R, Kurihara R, et al. In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia. Mol Biosyst. 2009;5:1306. doi:10.1039/b900880b
- Behr-Roussel D, Rupin A, Simonet S, Bonhomme E, Coumailleau S, et al. Effect of chronic treatment with the inducible nitric oxide synthase inhibitor N-iminoethyl-L-lysine or with L-arginine on progression of coronary and aortic atherosclerosis in hypercholesterolemic rabbits. Circulation. 2000;102:1033.
